Around 2,500 people attended Manchester’s #EnoughisEnough solidarity rally on Sunday.
Home Secretary Sajid Javid offered a message of support to the Jewish community.
Chair Stuart Ailion said anti-Semitism was “institutionalised” in Britain today.
“Make no mistake about it, it leaves our Jewish community feeling threatened, bullied, and vulnerable,” he said.
“We pay our respects to the victims of terror. We do not lay wreaths to the perpetrators of terror.”
Andy Burnham, the city’s mayor and his deputy Baroness Hughes were among a passionate crowd who heard addresses from numerous MPs pledging to root out anti-Semitism.
Speakers included Chief Rabbi Ephraim Mirvis, Dame Margaret Hodge and Dame Louise Ellman.
“I have lived my life as a secular Jew, but it is my heritage which has made me who I am,” exclaimed
Dame Margaret to huge cheers.
“I cannot, and I will not, forget”.
She added that Labour leader Jeremy Corbyn had to accept responsibility for what is going on in Labour today.
“He may be right to say that anti-Semitism exists elsewhere, but he is wrong to suggest that our mission to eradicate anti-Semitism from the Labour Party is simply an attempt to silence any criticism of the Israeli government.
“I will never accept anti-Semitism that is dressed up as something else, as a voice for Palestinian rights, when it is plain simple hatred of Jews.”
Chief Rabbi Mirvis noted that anti-Semitic incidents were at an all-time high in Britain but there was another Britain where you could walk the streets with a kippah without fear.
He posed the question, “Which Britain do you want to live in, in the future? A Britain that will make us proud, or bring us shame?”
Other speakers included Board of Deputies president Marie van der Zyl and Jewish Leadership Council chair Jonathan Goldstein
Mancunians were joined by supporters from London, Leeds, Liverpool, Glasgow, Sheffield and further afield Brighton, Plymouth and Canterbury at the rally.
Manchester Jews for Justice and Palestine Solidarity Campaign attracted small turn outs.